CD BioSciences

 CD BioSciences, a US-based biotechnology company focusing on the development of imaging technology, has announced the launch of its new range of In Vivo Imaging Reagents, including fluorescent imaging probes, fluorescent labeling dyes, fluorescent imaging panels, and fluorescent nanoparticles, designed to provide researchers with a non-invasive approach to visualize and quantify cellular and biological functions in living systems.

In vivo fluorescence imaging is a non-invasive method for visualizing and quantifying cellular and biological functions. Using these biospecific, validated fluorescent probes, dyes and panels, scientists can visualize disease pathogenesis and related biological processes in living systems. In certain preclinical studies, fluorescence can reveal disease processes and therapeutic effects earlier and more powerfully, making it an attractive alternative to standard imaging methods. There are many advantages to using in vivo fluorescence imaging for scientific research.

CD BioSciences now provides customers with fluorescent imaging probes, fluorescent label dyes, fluorescent imaging plates and fluorescent nanoparticles for scientific research. In addition, the company offers bioluminescent substrates and lentiviral particles, bioluminescent tumor cell lines, bioluminescent bacterial strains, and microbubble contrast agents. The company’s commitment to innovation and quality is evident in the development of these reagents, which are expected to revolutionize the field of in vivo imaging.

For example, the Pan Cathepsin Fluorescent Probe (Catalog NO: VIR030106) can be used for imaging various disease-related events. Proteases play an important role in protein regulation. Lysosomal proteases are a class of proteases whose altered activity predicts many disease-related processes such as cancer, inflammation, arthritis, and cardiovascular disease. The progression and severity of these diseases can be tracked and analyzed by detecting and quantifying normal and altered protease chelator protein activities in vivo. Pan Cathepsin fluorescent probes are versatile pan-trypsin-activatable near-infrared agents for imaging various disease-related events. These activatable probes are optically silent in the intact state and become highly fluorescent upon protease-mediated cleavage and activation.

Fluorescent Cell Labeling Dye (Catalog NO: VIR030201) allows the labeling and tracking of mammalian cells, including stem cells, T cells, and macrophages. This product is a near-infrared fluorescent lipophilic labeling dye that intercalates into the cell membrane. With high solubility and excellent stability, Fluorescent Cell Labeling Dye provides excellent brightness and uniform labeling, making it ideal for in vitro cell detection and longitudinal in vivo cell tracking in a variety of applications, including inflammation, immunology, and stem cell research.

CD BioSciences offers Oncology Fluorescent Imaging Panel (Catalog NO: VIR030306) to help customers maximize in vivo imaging preclinical cancer research. The development of novel, safer cancer therapies that target specific molecular targets and broader disease-related processes is critical in the fight against this disease. This new panel contains six carefully selected fluorescent probes that enable researchers to visualize and quantify various tumor-associated biological processes, providing a better understanding of the disease and aiding in the development of new cancer therapies.

For more information about CD BioSciences\' new range of In Vivo Imaging Reagents, please visit https://www.bioimagingtech.com/in-vivo-imaging-reagents.html.

About CD BioSciences

CD BioSciences is a biotechnology company committed to the development of imaging technology for many years. Its scientists can utilize high-content imaging, nanoparticle imaging, imaging flow cytometry, time-lapse imaging, and other techniques to image cell structure, cell migration, cell proliferation, pathogen infection mechanisms, and interactions between protein molecules.

CD BioSciences, a US-based biotechnology company focusing on the development of imaging technologies, is delighted to announce the addition of a new line of IHC Ancillaries to its product portfolio, including deparaffinators, retrievers and enzymes, washers and detergents, diluents and blockers, and mounting media. These ancillaries are developed to facilitate IHC research and diagnostics, enabling scientists, pathologists, and clinicians to achieve more accurate and reliable results.

Immunohistochemical staining depends on many different factors that can affect the staining results. Committed to advancing scientific discovery, CD BioSciences offers a wide range of reagents to ensure high quality staining and reliable, accurate results under optimal conditions each time antibodies are applied to tissue. These new IHC tools are available in component form and are easy to use. They are also supplied in a variety of sizes to meet the needs of different laboratories.

For example, the Retriever 20X with Citrate (Catalog NO: IHA040101) is designed for heat-induced epitope or nucleic acid retrieval procedures for immunohistochemistry (IHC), immunocytochemistry (ICC), immunofluorescence (IF), and in situ hybridization (ISH) of nucleic acids (CISH or FISH). It can be used to perform immuno or nucleic acid staining on formalin-fixed, paraffin-embedded tissue sections. This product can be utilized for any antigen or nucleic acid and promotes standardization of pretreatment procedures, resulting in more consistent and reliable results. It should be noted that this product is not intended for use in humans or animals.

Permanent Mounting Media (Catalog NO: IHA040109) is a non-toxic, biodegradable permanent mounting medium designed for the preservation of immunohistochemical and CISH stainings. It is ideal for mounting cell or tissue sections immunostained with horseradish peroxidase, alkaline phosphatase or other suitable enzymes and their substrate chromogens (e.g., DAB, HRP Black, and AP Blue). This medium is suitable for permanent mounting of cell or tissue samples treated with substrate-chromogen protectors to preserve solvent-sensitive substrate-chromogen stains such as AEC, Fast Red, HRP Blue, HRP Green, Alk Magenta, Alk Scarlet, Alk Red, and Alk Brown.

CD BioSciences offers Background Blocker (Catalog NO: IHA040302) to block or reduce antibody or antigen/nucleic acid-associated backgrounds that produce high backgrounds during IHC, CISH/FISH staining procedures. The reagent minimizes non-specific interactions that may be induced by antibodies or nucleic acids and promotes specific antigen-antibody binding. It can also be used as a diluent for different types of monoclonal, polyclonal, and control antibodies that produce a high background during IHC or CISH/FISH staining procedures.

CD BioSciences offers a series of ancillaries to help researchers and diagnosticians improve the efficiency and accuracy of their IHC assays, empowering scientists to unlock deeper insights into cellular processes and disease mechanisms. To learn more about the new products, please visit https://www.bioimagingtech.com/ihc-ancillaries.html.

About CD BioSciences

CD BioSciences is a biotechnology company committed to the development of imaging technology for many years. Its scientists can utilize high-content imaging, nanoparticle imaging, imaging flow cytometry, time-lapse imaging, and other techniques to image cell structure, cell migration, cell proliferation, pathogen infection mechanisms, and interactions between protein molecules.

CD BioSciences, a US-based biotechnology company focusing on the development of imaging technologies, proudly announces an extensive portfolio of Nervous System Tissue Microarrays designed to support neuroscience research. This comprehensive collection provides researchers with a unique resource to study various neurological conditions and accelerate their investigations into neurological diseases and disorders.

CD Bioscience has been developing imaging technologies for many years and uses high content imaging, nanoparticle imaging, imaging flow cytometry, time-lapse imaging and other technologies to image cellular structures, cell migration, cell proliferation, pathogen infection mechanisms and protein molecule interactions. In addition, the company has a team of professionals with extensive experience in the imaging field and can provide customers with personalized imaging services to meet their research needs in the fields of biology, microbiology, medicine and food.

CD BioSciences now offers a comprehensive portfolio of Nervous System Tissue Microarrays, including Brain Tissue Microarrays and Head & Neck Tissue Microarrays. This comprehensive offering provides researchers with a powerful tool for studying various neurological disorders, including brain tumors, head and neck cancers, and neurodegenerative diseases.

For example, Multiple Sites of Normal Brain Tissue Microarray, 80 Cases, 26 Cores (Catalog NO. NBCT003) is a tissue microarray consisting of normal brain tissue from multiple sites, including different regions of the brain. It contains 3 cases each of frontal lobe, apical lobe, occipital lobe, temporal lobe, midbrain, pons, medulla oblongata, thalamus opticus, cerebellum, hippocampus, callositas, optic nerves, and spinal cord tissue, and 1 case of caudate nucleus. Each case has duplicate cores for each block.

Head and Neck Cancer Tissue Microarray, 80 Cases, 80 Cores (Catalog NO. NBCT044) can be used for IHC, ISH and other routine histology procedures. This tissue microarray is created using head and neck cancer samples and tongue tissue, and it includes 57 cases of squamous cell carcinoma, 3 cases of undifferentiated carcinoma, 1 case of sarcomatoid carcinoma, 8 cases of metastatic squamous cell carcinoma, 7 cases of tongue tissue, 2 cases of salivary gland tissue, and 1 case each of sublingual gland tissue and parotid gland tissue. Each case has one nuclear core.

These microarrays allow researchers to conduct efficient and cost-effective studies on various neurological conditions, accelerating discoveries with the potential to improve patient outcomes. In addition, CD BioSciences is continually expanding its portfolio to provide scientists with more efficient tools to analyze multiple nervous system tissue samples simultaneously, facilitating in-depth investigations into disease mechanisms, biomarker discovery, and drug development.

With a focus on innovation and precision, CD BioSciences has developed state-of-the-art Nervous System Tissue Microarrays to allow scientists better study nervous tissue samples and advance neuroscience research. To learn more about the new products, please visit https://www.bioimagingtech.com/nervous-system-tissue-microarrays.html.

About CD BioSciences

CD BioSciences is a biotechnology company committed to the development of imaging technology for many years. Its scientists can utilize high-content imaging, nanoparticle imaging, imaging flow cytometry, time-lapse imaging, and other techniques to image cell structure, cell migration, cell proliferation, pathogen infection mechanisms, and interactions between protein molecules.

CD BioSciences, a US-based biotechnology company focusing on the development of imaging technologies, is proud to announce the launch of its new Multicolor Immunofluorescence Staining Kits. These kits empower researchers to achieve high-quality staining of tissues and cells utilizing 2-7 different colors, enabling more detailed and comprehensive analysis.

By providing researchers with the tools they need to achieve exceptional multicolor staining, CD BioSciences is committed to supporting groundbreaking discoveries across various fields of biological research. These new Multicolor Immunofluorescence Staining Kits are specifically designed for high-quality staining of human and small mammalian tissue sections and cells. With CD BioSciences’ advanced staining solutions, scientists can enhance their research by obtaining accurate and reliable results and unlock deeper insights into their samples.

Utilizing advanced technologies like Tyrosine Signal Amplification (TSA), these kits provide superior signal amplification and exceptional staining quality, particularly for human and small mammal samples. TSA utilizes HRP-conjugated secondary antibodies to catalyze the stable covalent binding of fluorescein substrate to antigen and amplify the fluorescent signal. In addition, the double immunofluorescence (IF) procedure is designed to detect the co-distribution of two different antigens in the same sample.

With these advancements, CD BioSciences\' Multicolor Immunofluorescence Staining Kits offer researchers a versatile and powerful solution for a wide range of applications. For example, the 7-Color mIF Staining Kit for Mouse Tissue, TSA (Catalog No. MCIS001) can be used for immunofluorescence staining of tissues, paraffin sections and TMA. This 7-color mIF Staining Kit utilizes TSA technology to efficiently detect 7 different antigens on mouse tissue or cell samples when paired with user-supplied rabbit primary antibodies. Multiple labeling can be achieved by using a heat repair method to remove non-covalently bound antibodies and performing a second round of incubation with the next primary antibody and another fluorogenic substrate.

2-Color IF Staining Kit for Mouse (Green) and Rabbit (Red) antibody (Catalog No. MCIS013) can be applied in IHC, ICC/IF, Flow, paraffin and frozen sections. The tissue microenvironment contains complex cellular components, and researchers can detect and identify different compositions through multiple immunofluorescence staining. This new 2-Color IF Staining Kit is paired with user-supplied mouse and rabbit primary antibodies to efficiently detect 2 different antigens on paraffin and frozen sections. The kit’s IF procedure is designed to detect the co-distribution of two different antigens in the same sample. Dual immunofluorescence staining allows simultaneous detection of mouse and rabbit primary antibodies. Please note that all of these kits are for research use only.

CD BioSciences offers Multicolor Immunofluorescence Staining Kits to empower researchers to explore the intricate details of cellular and tissue structures with unprecedented accuracy and sensitivity. To learn more about the new kits, please visit https://www.bioimagingtech.com/multicolor-immunofluorescence-staining-kits.html.

About CD BioSciences

CD BioSciences is a biotechnology company committed to the development of imaging technology for many years. Its scientists can utilize high-content imaging, nanoparticle imaging, imaging flow cytometry, time-lapse imaging, and other techniques to image cell structure, cell migration, cell proliferation, pathogen infection mechanisms, and interactions between protein molecules.